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Abstract
Pharmaceutical Care and Research: 2017; 17(4):294-297
DOI: 10.5428/pcar20170414
Analysis of off-label drug use and typical prescriptions in outpatients
1. SUN LeiQin(Department of Pharmacy,International Peace Maternity and Child Health Hospital Affiliated to School of Medicine,Shanghai Jiaotong University,Shanghai 200030,China qinc2008@126.com)
2. WU ZhiGang(Department of Pharmacy,International Peace Maternity and Child Health Hospital Affiliated to School of Medicine,Shanghai Jiaotong University,Shanghai 200030,China )
3. WANG JingWen(Department of Pharmacy,International Peace Maternity and Child Health Hospital Affiliated to School of Medicine,Shanghai Jiaotong University,Shanghai 200030,China )
4. LEI Ying(Department of Pharmacy,International Peace Maternity and Child Health Hospital Affiliated to School of Medicine,Shanghai Jiaotong University,Shanghai 200030,China )
ABSTRACT  Objective: To investigate the off-label drug use in outpatient prescriptions in the International Peace Maternity and Child Health Hospital Affiliated to School of Medicine,Shanghai Jiaotong University,and analyz typical prescriptions,so as to provide reference for rational use of drugs clinically.Methods: A total of 1800 prescriptions were included in the study and analyzed by retrospective survey method.Medication rationality of the prescriptions were analyzed from the terms of indications,dosage,administration frequency,administration route and applicable patients according to package inserts.Results: There were 303 off-label prescriptions in the 1800 prescriptions,accounting for 16.83%.In all the off-label drug use,supernumerary indications and over-dosage drug use accounted for high rates.There existed irrational use of drugs in some prescriptions.Conclusion: There is a certain percentage of off-label drug use in the hospital.Benefits as well as risks exist in clinical practice.With this reason,administrative departments and medical institutions should pay close attention to off-label drug use,so as to ensure safe and rational medication of drugs.
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Please cite this article as:
SUN LeiQin,WU ZhiGang,WANG JingWen,LEI Ying,. Analysis of off-label drug use and typical prescriptions in outpatients[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2017; 17(4): 294-297.
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